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KMID : 0361020060490100997
Korean Journal of Otolaryngology - Head and Neck Surgery
2006 Volume.49 No. 10 p.997 ~ p.1002
The Effect of Antibiotic Nebulizer Therapy for Treatment of Pediatric Chronic Rhinosinusitis
Min Kyung-Kun

Kim Sun-Young
Kang Il-Gyu
Cha Heung-Eog
Kim Seon-Tae
Abstract
Background & Objectives: The management of chronic recurrent rhinosinusitis in children has become controversial, because there are now various treatment modalities. We assessed nebulized antibiotic therapy, which had been studied as a treatment option in the postoperative infection in adult patients, for its effectiveness in children with chronic rhinosinusitis.

Subjects & Methods: We have selected 34 pediatric chronic rhinosinusitis patients who have received treatment for 3 months or 3 times for recent 6 months with oral antibiotics. They were treated with a nebulized antibiotic therapy for 4 weeks. We have compared pre-and post-treatment symptom scores, physical scores, and radiologic scores. After 6 months of follow up, infection free period was assessed.

Results: In 34 patients, 25 patients were selected for study. The symptoms and physical findings were improved in 76%, and the radiologic findings were also improved in 56%. Improvement in rhinorrhea, nasal obstruction, coughing and nasal swelling were significant. Mean infection free period was 13.7 weeks.

Conclusion: Nebulized antibiotic therapy might be considered as another therapeutic option for pediatric patients with chronic sinusitis who have failed to respond to oral antibiotics or who cannot tolerate them.
KEYWORD
Pediatric Chronic Rhinosinusitis, Nebulizer, Antibiotics
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